Biosynthesis of the indole alkaloids.
نویسندگان
چکیده
منابع مشابه
Biosynthesis of the indole and Colchicum alkaloids.
There has been enormous progress over the past fifteen years or so in our understanding of the ways in which complex natural products are synthesized in living systems. In the field of alkaloids, as elsewhere, research during the initial phase1 pin-pointed those substances which are used as the common building blocks, examples being acetic acid, ornithine and lysine for the reduced systems, and...
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The natural diversity of plant metabolism has long been a source for human medicines. One group of plant-derived compounds, the monoterpene indole alkaloids (MIAs), includes well-documented therapeutic agents used in the treatment of cancer (vinblastine, vincristine, camptothecin), hypertension (reserpine, ajmalicine), malaria (quinine), and as analgesics (7-hydroxymitragynine). Our understandi...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1965
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.53.5.901